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MBL Life science mbl protein concentration
Mbl Protein Concentration, supplied by MBL Life science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mbl protein concentration - by Bioz Stars, 2026-09
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Related Articles

Quantitative RT-PCR:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

Infection:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

Residue:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

Glycoproteomics:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

Control:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

Comparison:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

MANN-WHITNEY:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

Gene Expression:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

Amplification:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

Activation Assay:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

In Vivo:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

Staining:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

In Vitro:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).

Immunolabeling:

Article Title: Collectins: Innate Immune Pattern Recognition Molecules
Article Snippet: Two forms of MBL (MBL-A and MBL-C) were detected in rodents (Hansen et al. ; Drickamer et al. ), rabbits (Kawasaki et al. ; Kozutsumi et al. ) and rhesus monkeys (Mogues et al. ).

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury.
Article Snippet: We subjected mice with double (MBL−/−) or single (MBL-A−/− or MBL-C−/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo).

Article Title: Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.
Article Snippet: We subsequently analyzed the ho o enized snap-frozen kidn y cortex and the snap-frozen, strain r-isolat d g omeruli for the pr sence of MBL-A and MBL-C p ot ins.

Article Title: N-Linked Glycans Shape Skin Immune Responses during Arthritis and Myositis after Intradermal Infection with Ross River Virus
Article Snippet: L.O.D., limit of detection. (C) Quantitative RT-PCR of complement C3, MBL-C, and MBL-A in musculoskeletal tissues (C3: quadriceps and joints; MBL-C/MBL-A: quadriceps) at 10 dpi after infection with mam-RRV WT and mam-RRV E2DM .

Article Title: Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Article Snippet: Although this difference may not be mirrored in vivo, our data showing a decrease in ischemic volume and increase in neuronal viability in MBL-A −/− but not MBL-C −/− mice support the previous observations and suggest that MBL-A is the main activator of the complement system after brain ischemia.

Article Title: Intertwined pathways of complement activation command the pathogenesis of lupus nephritis.
Article Snippet: In aged MRL-lpr mice in which autoimmunity is most pronounced, high autoantibody titers and strong deposition of ICs in the glomeruli in association with deposition of C1q, C3, MBL-A and MBL-C have been noted suggesting that along with other complement pathways, the lectin pathway plays a significant role.77 MASPs are the enzymatic constituents of the lectin pathway and are associated with humoral pattern recognition molecules (MBL or ficolins).

Article Title: Decreased nematode clearance and anti-phosphorylcholine-specific IgM responses in mannose-binding lectin-deficient mice.
Article Snippet: However, in the spleen, absence of either MBL-A or -C resulted in significantly higher numbers of B220+CD21+CD23+ follicular B cells compared to C57Bl/6 mice (P < 0.05) (Figure 3c), while the absence of MBL-A resulted in a ~66% reduction in the total number of immature B220+CD21-CD23- B cells at (650,000±200,000 to ~200,000±42,000 cells) (P < 0.05) (Figure 3d).



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